At TRCoA we always tell students to split a guitar's signal path so we have a clean DI track that can later be reamped or processed through a digital amp simulation.
For guitar sessions that I do at home and send out to artists, I like to go one step further. I use a Radial JDV MK3 DI that has 3 outs. This lets me run one out to an amplifier that I mic up with a dynamic mic and a condenser mic. Then I take one out and run it through a tube pre that I then run into SGear. The last out is my totally clean DI.
When I send an artist my session work I am then able to send them 4 different options. I send the my amp microphone tracks (2), I send them an amp simulation that I pressed with effects (Delay, Reverb), I send them an amp simulation that I pressed with no effects (Clean Dry Amp), and finally I send them a totally clean DI signal that can be reamped or run into an amp simulation of choice.
With these options the artist has many options when it comes time to mix.